Month: January 2021

The lab of Kris Saha at the University of Wisconsin–Madison has developed an innovative combination of gene-editing tools and computational simulations that can be used to develop new strategies for editing genes associated with genetic disorders. In proof-of-concept experiments, the lab’s researchers efficiently corrected multiple mutations responsible for a rare metabolic disorder, known as Pompe disease, in cells …

Gene therapy has captured the public’s imagination as several products have now been approved for therapeutic use and hundreds more are being tested in clinical trials. In pursuit of this great potential, biomedical engineering associate professor Krishanu “Kris” Saha plans to lead the Grainger Institute for Engineering’s newest impact area, cell and gene therapy, by strengthening these possibilities, …